Expresión de búsqueda: A KINASE ANCHOR PROTEINS 
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Descriptor Inglés:   A Kinase Anchor Proteins 
Descriptor Español:   Proteínas de Anclaje a la Quinasa A 
Descriptor Portugués:   Proteínas de Ancoragem à Quinase A 
Categoría:   D12.644.360.024.065
D12.776.157.057.003
D12.776.476.024.069
Definición Inglés:   A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA. 
Nota Histórica Inglés:   2008 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número del Registro:   52783 
Identificador Único:   D054758 

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